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Buy Cheap Emsam Online

After you have selected the site for your patch, wash the area gently and well with soap and warm water. It is important to discuss all the risks of treating depression and also the risks of not treating it. After you apply a selegiline patch, you should wear it all the time until you are ready to remove it and put on a fresh patch. EMSAM is the reformulation of an oral MAOI, selegiline, into a skin patch form. Do not stop using transdermal selegiline without talking to your doctor. After you apply a selegiline patch, you should wear it all the time until you are ready to remove it and put on a fresh patch.

However, you should continue to use transdermal selegiline even if you feel well. Talk to your doctor often about your condition. EMSAM should be applied to dry, intact skin on the upper torso (below the neck and above the waist), upper thigh or the outer surface of the upper arm once every 24 hours. STS expands the range of pharmacological treatment options available to clinicians to treat major depressive disorder, in particular major depressive disorder with atypical features or treatment-resistant depression. This article discusses the mechanism of action of STS, summarizes efficacy and safety data from clinical trials, reviews drug and food interactions with STS and offers suggestions for use of STS in clinical practice.

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Your doctor should check your progress at regular visits. In an in vivo animal model, EMSAM exhibited antidepressant properties only at doses that inhibited both MAO-A and MAO-B in the brain. EMSAM is clearly an underutilized antidepressant which may be due partially to fears about MAOI side effects, clinical trials that did not address enough clinical questions, inadequate analyses of data, minimal postmarketing studies, and inadequate marketing in general. Selegiline is an irreversible, selective monoamine oxidase (MAO) type B inhibitor. Dry the area with a clean dry towel.

Recommended dosage

Also, tell your surgeon that you take EMSAM. Do not apply more patches or apply patches more often than prescribed by your doctor. Do not stop using transdermal selegiline without talking to your doctor. Antidepressants increased the risk of suicidal thinking and behavior (suicidality) in short-term studies in children and adolescents with major depressive disorder (MDD) and other psychiatric disorders. The efficacy and safety of STS has been established in short and long-term clinical trials. Do not apply selegiline patches to skin that is hairy, oily, irritated, broken, scarred, or calloused.

  • The efficacy and safety of STS has been established in short and long-term clinical trials. As with other psychoactive drugs, EMSAM may have the potential to impair judgment, thinking, or motor skills.
  • So why wasn't oral selegiline marketed to psychiatrists? Never cut an EMSAM patch into smaller pieces to use.
  • Read all patient information, medication guides, and instruction sheets provided to you.

Side effects

Ultimately, a study comparing EMSAM to other antidepressants in MDD focusing on efficacy and tolerance would be clinically important. Since death has been reported following overdosage with MAOI agents, hospitalization with close monitoring during this period is strongly recommended. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself. Some young people have thoughts about suicide when first taking an antidepressant. Know all of the medicines that you or your family member takes. Follow all directions on your prescription label. Do not change your patch removal schedule.

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Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. After you have selected the site for your patch, wash the area gently and well with soap and warm water. Use EMSAM exactly as prescribed by your doctor. Antidepressants are medicines used to treat depression and other illnesses.

Emsam facts:

  • You may leave the patch on while bathing, showering, or swimming. Suicide is a known risk of depression and certain other psychiatric disorders, and these disorders themselves are the strongest predictors of suicide.
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  • After you have selected the site for your patch, wash the area gently and well with soap and warm water. The pharmaceutical industry should not be shortsighted when developing a novel drug for the treatment of a highly prevalent disorder such as MDD.
  • Although selegiline was never FDA-approved as an antidepressant in this country, there has been ample clinical experience and research data demonstrating that it is an effective antidepressant at doses between 30 and 60 mg a day (Bodkin et al, Psychiatric Annals 2001; 31:385-391). Patients with major depressive disorder (MDD), both adult and pediatric, may experience worsening of their depression and/or the emergence of suicidal ideation and behavior (suicidality) or unusual changes in behavior, whether or not they are taking antidepressant medications, and this risk may persist until significant remission occurs.
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  • The pharmaceutical industry should not be shortsighted when developing a novel drug for the treatment of a highly prevalent disorder such as MDD. There has been a long-standing concern, however, that antidepressants may have a role in inducing worsening of depression and the emergence of suicidality in certain patients during the early phases of treatment.
  • Families and caregivers should be advised for the need for close observation and communication with the prescriber. Wash your hands with soap and water after applying an Emsam patch, and after removing one.
  • After stopping treatment with drugs contraindicated with selegiline, a time period equal to 4 to 5 half-lives (approximately 1 week) of the drug or any active metabolite should elapse before starting therapy with selegiline.
  • All human pregnancies, regardless of drug exposure, have a background rate of 2% to 4% for major malformations, and 15% to 20% for pregnancy loss. Choose a time of day that works best for you.
emsam vs selegiline

On the other hand, many potential advantages of EMSAM are not highlighted enough in the literature and by pharmaceutical companies which might have increased clinical interest and utilization of the antidepressant. The EMSAM patch is a unique monoamine oxidase inhibitor (MAOI) being the only antidepressant utilizing a transdermal delivery system. The efficacy and safety of STS has been established in short and long-term clinical trials. Most of these effects were seen at the high dose in both rats and rabbits. Use EMSAM exactly as prescribed by your doctor. EMSAM should be used in pregnancy only if the potential benefit justifies the potential risk to the fetus.

Precautions

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Ask your doctor or pharmacist if you have any questions. All pediatric patients being treated with antidepressants for any indication should be observed closely for clinical worsening, suicidality, or unusual changes in behavior, especially during the initial few months of a course of drug therapy, or at time of dose changes, either increases or decreases. Your family or other caregivers should also be alert to changes in your mood or symptoms. In a pre-natal and post-natal development study, transdermal administration of selegiline in rats at doses 8, 24, and 60 times MRHD produced delayed neurobehavioral and sexual development in pups. Selegiline prevents the breakdown of chemicals in the brain that are often imbalanced in people with depression.

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