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by reducing the doses given during the day and possibly increasing the evening dose). Overdose symptoms may include muscle weakness, vomiting, drowsiness, dilated or pinpoint pupils, weak or shallow breathing, fainting, or coma. In patients with epilepsy, the clinical state and electroencephalogram should be monitored at regular intervals, since deterioration in seizure control and EEG have been reported occasionally in patients taking Lioresal. Lioresal should be used with caution where spasticity is utilized to sustain upright posture and balance in locomotion or whenever spasticity is utilized to obtain increased function. Tell your doctor if your condition does not improve or if it worsens. LIORESAL INTRATHECAL is indicated for use in the management of severe spasticity. Oral or enteral baclofen alone should not be relied upon to halt the progression of intrathecal baclofen withdrawal. Lioresal should be administered to end stage renal failure patients only if the expected benefit outweighs the potential risk.

The liquid may be particularly suitable for children or those adults who are unable to take tablets. Withdrawal symptoms are more likely if baclofen is used for long periods of time (more than a couple of months) and can occur from low or high doses. Check the label on the medicine for exact dosing instructions. If too high a dose is initiated or if the dosage is increased too rapidly side effects may occur. Drinking alcohol can increase certain side effects of baclofen.

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Direct injection into the catheter through the catheter access port may cause a life-threatening overdose. It is also used by compounding pharmacies in topical pain creams as a muscle relaxant. Disposal If your doctor tells you to stop taking Lioresal or the expiry date on the medicine has passed, ask your pharmacist what to do with any tablets you have left over. Never give it to someone else. If you have ever had an allergic reaction to a medicine.

Recommended dosage

If you have to take Lioresal during pregnancy your baby may have convulsions just after delivery. Once the maximum recommended dose has been reached, if the therapeutic effect is not apparent within 6 weeks a decision whether to continue with Lioresal should be taken. It is not known if this medicine is found in breast milk. Using baclofen may increase your risk of developing an ovarian cyst. If you do not understand the instructions on the label, ask your doctor or pharmacist for help. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines. Drug withdrawal reactions including postnatal convulsions in neonates following intra-uterine exposure to oral baclofen, have been reported.

  • Baclofen stimulates gastric acid secretion. Discuss the risks and benefits with your doctor.
  • Alcohol is not compatible with the reception Lioresal.
  • The Principle of Operation Lioresal bloodstream reaches the spinal cord, its GABA receptors. LIORESAL INTRATHECAL is indicated for use in the management of severe spasticity.

Side effects

Tell your doctor if you are pregnant or plan to become pregnant while using this medication. This medicine has been prescribed for you. Acute withdrawal symptoms can be stopped by recommencing baclofen. Therefore, except for serious adverse reactions, the dose should be reduced slowly when the drug is discontinued. During treatment with Lioresal, neurogenic disturbances affecting the emptying of the bladder may improve, whereas in patients with pre-existing sphincter hypertonia, acute retention of urine may occur.

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Please read this leaflet carefully before you start to take your medicine. Report any side effects promptly to your doctor. Call your doctor for medical advice about side effects. As a general rule, nursing should not be undertaken while a patient is on a drug since many drugs are excreted in human milk.

Lioresal facts:

  • lioresal 10mg baclofen
  • No deje de tomarlo salvo el consejo de su doctor. Proper storage of Lioresal: General information: This information should not be used to decide whether or not to take Lioresal or any other medicine.
  • You should not breast-feed while you are using baclofen. Treatment: In the alert patient, empty the stomach promptly by induced emesis followed by lavage.
  • Do not increase your dose or take it more often than prescribed. Reservoir refilling must be performed by fully trained and qualified personnel following the directions provided by the pump manufacturer. Do not reuse needles, syringes, or other materials.
  • Proper storage of Lioresal: General information: This information should not be used to decide whether or not to take Lioresal or any other medicine.
  • The information in this leaflet was last updated on the date listed on the final page. If you are or will be breast-feeding while you use Lioresal, check with your doctor.
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If you notice other effects not listed above, contact your doctor or pharmacist. Do not take extra medicine to make up the missed dose. The following gradually increasing dosage regimen is suggested, but should be adjusted to suit individual patient requirements. Keep this product, as well as syringes and needles, out of the reach of children and pets.


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Maintenance dose averages 300-800 micrograms each day. Following appropriate responsiveness, adjust dosage to twice the screening dose and give over 24 hours. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Because LIORESAL is primarily excreted unchanged through the kidneys, it should be given with caution in patients with renal insufficiency, and generally with a reduced dose. Therefore, Lioresal should not be used during pregnancy unless the expected benefit outweighs the potential risk to the foetus. For children up to 4 years it is also contraindicated.

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